Phagocytosis of Group B Streptococcus by Neutrophils from Newborn Infants

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Nonopsonic phagocytosis of group C Neisseria meningitidis by human neutrophils.

Although complement-mediated bactericidal activity in serum has long been known to be very important in host defense against Neisseria meningitidis, recent studies have shown that opsonic phagocytosis by neutrophils is also important. The purpose of this study was to determine if endemic group C N. meningitidis strains were susceptible to nonopsonic (complement- and antibody-independent) phagoc...

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Serotype Distribution and Invasive Potential of Group B Streptococcus Isolates Causing Disease in Infants and Colonizing Maternal-Newborn Dyads

BACKGROUND Serotype-specific polysaccharide based group B streptococcus (GBS) vaccines are being developed. An understanding of the serotype epidemiology associated with maternal colonization and invasive disease in infants is necessary to determine the potential coverage of serotype-specific GBS vaccines. METHODS Colonizing GBS isolates were identified by vaginal swabbing of mothers during a...

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ژورنال

عنوان ژورنال: Pediatric Research

سال: 1983

ISSN: 0031-3998,1530-0447

DOI: 10.1203/00006450-198305000-00010